Article ID Journal Published Year Pages File Type
5897201 Cytokine 2013 12 Pages PDF
Abstract
► The fungal lactones antagonized TGF-β cellular effects. ► Oxacyclododecindione showed a highly potent inhibition of TGF-β signaling. ► All compounds inhibited DNA binding of the activated Smad transcription factors.
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Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Endocrinology
Preview
Inhibition of TGF-β signaling by the fungal lactones (S)-curvularin, dehydrocurvularin, oxacyclododecindione and galiellalactone
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