Article ID Journal Published Year Pages File Type
5897207 Cytokine 2013 6 Pages PDF
Abstract
► Proteins by the oral route can have immuno-activity. ► Thyrotropin releasing factor (TRH) has intrinsic immuno-activity. ► Murine experimental autoimmune encephalomyelitis is an animal model for human disease multiple sclerosis. ► Thyrotropin releasing factor (TRH) administered orally inhibits murine experimental autoimmune encephalomyelitis. ► Adoptive transfer of lymphocytes from TRH fed donors into immunized recipients inhibits EAE.
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