Maintenance of CMV-specific CD8+ T cell responses and the relationship of IL-27 to IFN-Î³ levels with aging

Article ID	Journal	Published Year	Pages	File Type
5897240	Cytokine	2013	6 Pages	PDF

Abstract

âº CMV-specific CD8+ T cell proliferation and cytokine production did not alter with age. âº Young and elderly people had similar levels of plasma IL-27. âº CMV-infected young and elderly people had an increased trend of plasma IL-27 levels. âº Correlation of IL-27 and IFN-Î³ occurred irrespective of age and CMV-infectious status.

Keywords

T helper IL-27 TCr EBI3 EAE DCs PBMCs CFSE natural killer CD8+ T cells collagen-induced arthritis experimental allergic encephalitis Human standard error of mean Carboxyfluorescein diacetate Aging peripheral blood mononuclear cells Dendritic cells CIA cytomegalovirus CMV Cytomégalovirus (CMV)SEM T cell receptor