| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5897242 | Cytokine | 2013 | 8 Pages |
Abstract
⺠Osteopontin is involved in the initiation of immune responses to diverse pathogens. ⺠Trypanosoma cruzi infection induces osteopontin release from murine macrophages. ⺠In vivo neutralization of osteopontin augments mice susceptibility to infection. ⺠In vivo neutralization of osteopontin reduces Th1 and Th17 cytokine production. ⺠Endogenous osteopontin helps regulate protective Th1 and Th17 responses to T. cruzi.
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Authors
Miguel H. SantamarÃa, Ricardo S. Corral,