Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5897267 | Cytokine | 2013 | 6 Pages |
Abstract
⺠APRIL induces HoxC4 and AID mRNA expression in mouse B cells. ⺠APRIL increases HoxC4 promoter activity in mouse B cells. ⺠Second NF-κB-binding element (NBE2) is essential for the HoxC4 promoter activation. ⺠APRIL enhances binding of NF-κB to the HoxC4 promoter NBE2 region. ⺠Overexpression of NF-κB increases APRIL-induced HoxC4 promoter activity.
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Authors
Seok-Rae Park, Pyeung-Hyeun Kim, Kyu-Seon Lee, Sang-Hoon Lee, Goo-Young Seo, Yung-Choon Yoo, Junglim Lee, Paolo Casali,