Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5897300 | Cytokine | 2012 | 5 Pages |
Abstract
⺠Obesity is associated with a chronic low inflammatory state. ⺠Genetic factors associated with obesity are also associated with serum monocyte chemoattractant protein-1 (MCP-1) levels. ⺠A GWAS in obese Hispanic children showed strong association between DARC gene and serum MCP-1 levels. ⺠Serum MCP-1 concentration was also significantly associated with CCR3 and CARD9 genes. ⺠The association of DARC with serum MCP-1 levels replicates previous GWAS results.
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Authors
V. Saroja Voruganti, Sandra Laston, Karin Haack, Nitesh R. Mehta, C. Wayne Smith, Shelley A. Cole, Nancy F. Butte, Anthony G. Comuzzie,