Article ID Journal Published Year Pages File Type
5897300 Cytokine 2012 5 Pages PDF
Abstract
► Obesity is associated with a chronic low inflammatory state. ► Genetic factors associated with obesity are also associated with serum monocyte chemoattractant protein-1 (MCP-1) levels. ► A GWAS in obese Hispanic children showed strong association between DARC gene and serum MCP-1 levels. ► Serum MCP-1 concentration was also significantly associated with CCR3 and CARD9 genes. ► The association of DARC with serum MCP-1 levels replicates previous GWAS results.
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Life Sciences Biochemistry, Genetics and Molecular Biology Endocrinology
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