| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5897366 | Cytokine | 2013 | 9 Pages |
Abstract
⺠Melphalan (MEL) reduced mitotic rate when administered to mice bearing melanoma. ⺠Tnfa (TNF) improved necrosis and reduced mitotic rate in B16F10 derived tumors. ⺠MEL and MEL + TNF promoted tumor growth arrest and prolonged survival of mice. ⺠TNF induced necrosis did not translate in improved survival. ⺠Treatment with MEL, TNF, or MEL + TNF promoted differential expression of 118 genes.
Keywords
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Endocrinology
Authors
Vladmir Cláudio Cordeiro de Lima, Alex Fiorini de Carvalho, Mariana Morato-Marques, Vivian Lika Hashimoto, Graziela Machado Gruner Turco Spilborghs, Sarah Martins Marques, Gilles Landman, Cesar Torres, Karina Braga Ribeiro, Helena Brentani,