| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5897634 | Cytokine | 2013 | 11 Pages |
Abstract
⺠Naturally existing CD4 T cells that produce IL-2 were found in variety of tissues of healthy mice. ⺠Cells produced IL-2 are mostly CD4+, CD44+, CD62L+, and ICOS+. ⺠The frequency of cells produce IL-2 is highest in lamina propria. ⺠IL-2 produced cells are not detectable in newborn mice and become detectable 5 days after birth. ⺠A significant fraction of IL-2 produced cells co-produce IL-10 and IFN-γ.
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Authors
Mutsumi Yamamoto, Yoichi Seki, Kazuyuki Iwai, Iei Ko, Alicia Martin, Noriko Tsuji, Shuji Miyagawa, Robert B. Love, Makio Iwashima,