Article ID Journal Published Year Pages File Type
5897637 Cytokine 2013 7 Pages PDF
Abstract
► U50,488H modulates TLR4/NF-κB signaling in the rat heart subjected to MI/R. ► U50,488H decreased NF-κB expression in the ischemia and risking area of MI/R. ► U50,488H down-regulated TLR4 gene and protein expressions in the MI/R heart. ► U50,488H inhibited TNF-a levels in the serum and MI/R tissue. ► U50,488H inhibited neutrophil infiltration in the heart subjected to MI/R.
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Life Sciences Biochemistry, Genetics and Molecular Biology Endocrinology
Preview
κ-Opioid receptor stimulation modulates TLR4/NF-κB signaling in the rat heart subjected to ischemia-reperfusion
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