Article ID Journal Published Year Pages File Type
5897642 Cytokine 2013 14 Pages PDF
Abstract
► IL-17 is expressed constitutively within retinal tissues of healthy C57BL/6 mice. ► IL-17 levels in whole splenic cells increase during the progression of MAIDS. ► Cell populations other than CD4+ T cells contribute to IL-17 production during MAIDS. ► MCMV infection downregulates IL-17 production during health and MAIDS. ► MCMV-induced downregulation of IL-17 may involve upregulation of SOCS-3 and IL-10.
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