Article ID Journal Published Year Pages File Type
5897645 Cytokine 2013 9 Pages PDF
Abstract
► Both leptin and estrogen regulate the metabolism of chondrocytes in the growth plate. ► Simultaneous expressions of Ob-Rb and ERα or ERβ in ATDC5 cells were observed. ► The crosstalk between leptin and estrogen receptor was differentiation stage specific. ► Leptin influenced the production of extracelluar matrix partly via ERα and ERα/ERβ.
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Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Endocrinology
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Stage specific effect of leptin on the expressions of estrogen receptor and extracellular matrix in a model of chondrocyte differentiation
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