| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5897816 | Cytokine | 2013 | 8 Pages |
Abstract
IL-32 acts as a proinflammatory factor and may be implicated in the inflammatory cascade contributing to atherosclerosis. By promoting the synthesis of matrix metalloproteinases, it may further contribute to plaque instability. Further studies are warranted to investigate whether IL-32 may serve as a potential therapeutic target in fighting atherosclerosis.
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Authors
Bas Heinhuis, Calin D. Popa, Berry L.J.H. van Tits, Soo-Hyun Kim, Patrick L. Zeeuwen, Wim B. van den Berg, Jos W.M. van der Meer, J. Adam van der Vliet, Anton F.H. Stalenhoef, Charles A. Dinarello, Mihai G. Netea, Leo A.B. Joosten,