| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5897869 | Cytokine | 2013 | 4 Pages |
Abstract
⺠We examine pleiotrophin (PTN) effect on capillary sprouting during aging. ⺠Capillary sprouting is lower in senescent aortic rings as compared to adults. ⺠Capillary formation is improved after PTN treatment in explanted vessels at all ages. ⺠Angiogenic effects of PTN and VEGF are of the same extent in senescent vessels. ⺠PTN could be a promising therapeutic agent for revascularization therapy during aging.
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Authors
Sophie Besse, Romain Comte, Sophie Fréchault, José Courty, Joël de Leiris, Jean Delbé,