Article ID Journal Published Year Pages File Type
5897872 Cytokine 2013 6 Pages PDF
Abstract
► We compared the effects of several cytokine combinations on NK cell function. ► IL21 + IL2 induced a synergistic effect on degranulation but not on cytokine production. ► Optimal cytokine production was induced by IL21 + IL15. ► Higher production of TNFα was shown in the CD56dim subset after NKp46 engagement. ► Different cytokines combined with selected NK receptor stimuli can help to dissect NK responses.
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