Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5897872 | Cytokine | 2013 | 6 Pages |
Abstract
⺠We compared the effects of several cytokine combinations on NK cell function. ⺠IL21 + IL2 induced a synergistic effect on degranulation but not on cytokine production. ⺠Optimal cytokine production was induced by IL21 + IL15. ⺠Higher production of TNFα was shown in the CD56dim subset after NKp46 engagement. ⺠Different cytokines combined with selected NK receptor stimuli can help to dissect NK responses.
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Authors
Stefania Varchetta, Barbara Oliviero, Domenico Mavilio, Mario U. Mondelli,