| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5897884 | Cytokine | 2013 | 5 Pages |
Abstract
⺠We demonstrate that IFN-γ suppressed H3K4 dimethylation at the intronic enhancer region of the Il4 gene. ⺠The IFN-γ-mediated suppression of permissive chromatin remodeling was IFN-γ-R-, STAT1-, and T-bet-dependent. ⺠Our study reveals a novel mechanism of how Th1 cells silence the Il4 gene.
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Authors
Jun Nishida, Yapeng Li, Yonghua Zhuang, Zan Huang, Hua Huang,