| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5897896 | Cytokine | 2013 | 10 Pages |
Abstract
⺠Activated TCD4+ cells are detected in human atherosclerotic plaques. ⺠We found that plaques of human carotid express TH1/2/17/22 mRNA related markers. ⺠IL-23+, TGF-β, IL-1β and IL-18+ macrophages/foam cells were also detected. ⺠Atheroma infiltrating cells were TCD4+ IFN-γ+/IL-17+/IL-4+ and IL-22+.⺠Distinct cells subsets may contribute to atheroma progression and destabilization.
Keywords
AHRTGF-βCCL20IL-23TH22Th1RORγtTh17SCIDIFN-γCCRGATA-3T-box expressed in T cellsAtherosclerosisinflammationCarotid endarterectomyinterferon-gammainterleukintumor necrosis factor-αT-betT helper cellTNF-αlow density lipoproteinLDLSCID, Severe combined immunodeficiencyGATA binding protein 3aryl hydrocarbon receptorCC chemokine receptor
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Authors
Rômulo Tadeu Dias Oliveira, Rosiane Maria Silva, Fabio Haach Teo, Marcela Franco Mineiro, Maria Carolina Ferreira, Albina Altemani, Ronei Luciano Mamoni, Fábio Husseman Menezes, Maria Heloisa Souza Lima Blotta,