Article ID Journal Published Year Pages File Type
5897919 Cytokine 2012 8 Pages PDF
Abstract
► Influence of IGF-I on functional properties of neonatal immune cells. ► IGF-I suppresses Th1 cytokines IL-2 and IFN-γ. ► IGF-I receptor is upregulated upon stimulation of neonatal lymphocytes. ► DNA binding activity of AP-1 and NFκB was decreased by IGF-I.
Keywords
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Endocrinology
Preview
Insulin-like growth factor-I regulates the neonatal immune response in infection and maturation by suppression of IFN-γ
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