Article ID Journal Published Year Pages File Type
5897933 Cytokine 2012 7 Pages PDF
Abstract
► The study was conducted on well characterized RM patients and healthy controls. ► CTLA-4 +49A/G, CTLA4 (AT)n 3′UTR, TNF-α(-308G/A, -238G/A) polymorphisms were studied. ► GG and AA genotype of CTLA4 +49A/G and TNF-α-308 were RM causative. ► 104, 106, 110 and 116 bp alleles of CTLA-4 (AT)n 3′UTR repeat showed risk association. ► GA and AG haplotypes of TNF-α were low risk associated haplotypes.
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