Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5897959 | Cytokine | 2012 | 8 Pages |
Abstract
⺠IL-6 induces STAT5 phosphorylation in CD4 T cells. ⺠IL-6 up-regulates the STAT5-regulated CIS mRNA level in CD4 T cells. ⺠“Inflammatory” IL-6 levels are required to induce STAT5 activation.
Keywords
Th17TGF-βpStatCytokine-inducible SH2-containing proteiniTregsSTAT5TFHSTAT3TregG-CSFRABSmAbsMFICISAPCallophycocyaninSTATantibodiesinterleukin-6Transforming Growth Factor BetaCD4 T cellsFollicular helper T cellsT regulatory cellT helper cellsphycoerythrinsignal transducers and activators of transcriptionmean fluorescence intensityMonoclonal antibodiesJAKJanus kinasesgranulocyte colony-stimulating factor receptor
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Authors
Aurélie Jeanne Tormo, Marie-Claude Letellier, Mukut Sharma, Greg Elson, Sandrine Crabé, Jean-François Gauchat,