Article ID Journal Published Year Pages File Type
5898002 Cytokine 2012 9 Pages PDF
Abstract
► Fibronectin inhibits CpG motif-dependent cytokine production in macrophages. ► Fibronectin does not bind to pDNA in the presence of divalent cations. ► Integrin α5β1 does not involved in the inhibitory effect of fibronectin. ► Fibronectin does not affect the cellular uptake of pDNA. ► Fibronectin and pDNA are colocalized in the same intracellular compartment.
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