Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5898002 | Cytokine | 2012 | 9 Pages |
Abstract
⺠Fibronectin inhibits CpG motif-dependent cytokine production in macrophages. ⺠Fibronectin does not bind to pDNA in the presence of divalent cations. ⺠Integrin α5β1 does not involved in the inhibitory effect of fibronectin. ⺠Fibronectin does not affect the cellular uptake of pDNA. ⺠Fibronectin and pDNA are colocalized in the same intracellular compartment.
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Authors
Hiroyuki Yoshida, Makiya Nishikawa, Sachiyo Yasuda, Hiroyasu Toyota, Tsuyoshi Kiyota, Yuki Takahashi, Yoshinobu Takakura,