Article ID Journal Published Year Pages File Type
5898036 Cytokine 2012 8 Pages PDF
Abstract
► The ER is central for lipid synthesis, protein folding and protein maturation. ► Conditions interfering with ER function are collectively known as ER stress. ► The role of ER stress in the immune system is an emerging therapeutic target. ► The list of signalling pathways that act in synergy with TLRs now include ER stress. ► Targeting various components of ER stress is a promising therapeutic strategy.
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