Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5898036 | Cytokine | 2012 | 8 Pages |
Abstract
⺠The ER is central for lipid synthesis, protein folding and protein maturation. ⺠Conditions interfering with ER function are collectively known as ER stress. ⺠The role of ER stress in the immune system is an emerging therapeutic target. ⺠The list of signalling pathways that act in synergy with TLRs now include ER stress. ⺠Targeting various components of ER stress is a promising therapeutic strategy.
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Authors
M.W. Lawless, C.M. Greene,