Article ID Journal Published Year Pages File Type
5898048 Cytokine 2012 9 Pages PDF
Abstract
► Disruption of tight junction relates to TNF-α induced Caco-2 cell hyperpermeability. ► NF-κB mediates TNF-α signal in above process. ► Early NF-κB activation may not be the downstream but be upstream affaires of cytoskeleton rearrangement. ► NF-КB/MLCK/MLC phosphorylation is crucial to regulate tight junction of Caco-2 cell.
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Authors
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