| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5898078 | Cytokine | 2012 | 7 Pages |
Abstract
⺠21 Days HDBR decreases production of IL-2, IFN-γ and TNF-α in whole-blood stimulation assay. ⺠HDBR is associated with an unexpected high incidence of infections. ⺠Head-down bed rest (HDBR) confirms some spaceflight impact on human immunity.
Keywords
HDBRPBSTNFFOXP3KHCO3TregsPHAPPDPhytohemagglutininPBMCsCMIBed restEBVCell-mediated immunityimmunoglobulin interferonIFNinterleukinPotassium bicarbonateBody massHead-down bed restMicrogravityperipheral blood mononuclear cellsT cellsRegulatory T cellscytomegalovirusCMVtumor necrosis factorPhosphate-buffered salinepurified protein derivativeNASApolymerase chain reactionPCREpstein–Barr virusforkhead box protein 3nuc
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Authors
Jens Kelsen, Lars Erik Bartels, Anders Dige, Christian Lodberg Hvas, Petra Frings-Meuthen, Gisela Boehme, Marianne Kragh Thomsen, Morten Fenger-Grøn, Jens Frederik Dahlerup,