Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5898098 | Cytokine | 2012 | 9 Pages |
Abstract
⺠We examined cytokines/chemokines response patterns in two murine stains following TBI. ⺠Different cytokines have different plasma concentrations at baseline. ⺠Twelve cytokines/chemokines showed strain-specific response patterns. ⺠Ten cytokines/chemokines exhibited similar temporal patterns. ⺠Serial measurements will be necessary if temporal cytokine patterns are to act as a biodosimeter.
Keywords
LD50/30MmpssTNF-R1TARC/CCL17IGF-1TBITIMP-1TSLPGM-CSFSCFgranulocyte–macrophage colony stimulating factorPDGFTotal body irradiationinsulin-like growth factor-1ionizing radiationthymus and activation-regulated chemokineRadiation toleranceCytokinesgranulocyte colony-stimulating factorVascular endothelial growth factorVascular Endothelial Growth Factor (VEGF)platelet-derived growth factorStem Cell FactorG-CSFThymic stromal lymphopoietinMetalloproteinasesChemokines
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Authors
Mei Zhang, Liangjie Yin, Kunzhong Zhang, Weimin Sun, Shanmin Yang, Bingrong Zhang, Peter Salzman, Wei Wang, Chaomei Liu, Sadasivan Vidyasagar, Lei Zhang, Shaoqing Ju, Paul Okunieff, Lurong Zhang,