Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5898110 | Cytokine | 2012 | 5 Pages |
Abstract
⺠The expression of TLR5 was observed in the colon epithelium. ⺠Inflammatory bowel disease (IBD) patients express high levels of TLR5 in the colon epithelium. ⺠Flagellin activates TLR5 increases TNFα production in the colon epithelium. ⺠The autocrine TNFα compromises intestinal epithelial barrier function.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Endocrinology
Authors
Qun-Ying Wang, Ai-Min Sun, Jian Song, Ye Chen, Ji-De Wang, Chuan-Gang Li,