Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5898119 | Cytokine | 2012 | 7 Pages |
Abstract
⺠We confirm for the first time that IL-3 and IL-4 are critical for IL-33 intracrine in various types of cells. ⺠Macrophage is not the only target of IL-3 and IL-4 in the heterogeneous peritoneal exudate cells. ⺠Macrophage is not essential for the in vivo constitutive expression of IL-33 in various tissues. ⺠IL-3 and IL-4 induce IL-33 intracrine in the homogeneous cell population as fibroblasts and mast cells. ⺠Up to 100 cytokines were screened, but none of them stimulated the release of IL-33 from the cultured cells.
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Authors
Wei-Hua Zhao, Zhi-Qing Hu,