Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5898145 | Cytokine | 2011 | 8 Pages |
Abstract
⺠A novel sPD-L1 ELISA was developed with well specificity, precision and stability. ⺠PD-L1+ cell lines produce high levels of sPD-L1 protein. ⺠The concentration of sPD-L1 in human serum increases in an age-dependent manner. ⺠Matrix metalloproteinase inhibitor (MMPI) could suppress sPD-L1 production. ⺠The circulating sPD-L1 could specially bind to PD-1 receptor.
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Authors
Yongjing Chen, Qin Wang, Bimin Shi, Ping Xu, Zhenhua Hu, Lixiong Bai, Xueguang Zhang,