| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5898162 | Cytokine | 2011 | 7 Pages |
Abstract
⺠There are gender related differences following major trauma and sepsis. ⺠Estradiol mediates beneficial effects. ⺠Finasteride increases estradiol levels by inhibition of 5α-reductase after hemorrhage and sepsis in mice. ⺠After trauma-hemorrhage and subsequent sepsis, finasteride mediates protective effects.
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Authors
Christian Zeckey, Hagen Andruszkow, Claudia Neunaber, Michael Frink, Bastian Schirmer, Philipp Mommsen, Tanja Barkhausen, Christian Krettek, Frank Hildebrand,