Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5898229 | Cytokine | 2012 | 8 Pages |
Abstract
⺠Hematopoietic stem cells (HSCs) functionally respond to Toll-like receptor (TLR) ligation. ⺠TLR ligation of HSCs alters self-renewal and differentiation activities. ⺠HSCs directly respond to inflammatory cytokines associated with pathogen exposure. ⺠TLR ligation is associated with human disease and may be therapeutically manipulated.
Keywords
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Authors
Julie R. Boiko, Lisa Borghesi,