| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5898236 | Cytokine | 2012 | 9 Pages |
Abstract
⺠CoPoIFN-α is a recombinant non-naturally occurring porcine IFN-α. ⺠The antiviral activity of CoPoIFN-α was higher than wild-type PoIFN-α for VSV, PRV and PRRSV. ⺠The antiproliferative activity of CoPoIFN-α was higher than that of PoIFN-α. The mRNA levels of two ISGs were also enhanced. ⺠The high activity of CoPoIFN-α was probably due to the enhanced interactions between the IFN-α and the receptor.
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Authors
Li Huang, Rui-bing Cao, Ning Wang, Ke Liu, Jian-chao Wei, Hassan Isahg, Li-jie Song, Wei-yong Zuo, Bin Zhou, Wei-wu Wang, Xiang Mao, Pu-yan Chen,