| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5898284 | Cytokine | 2011 | 6 Pages |
Abstract
⺠IL-13 is important in the pathogenesis of systemic sclerosis (SSc). ⺠Peripheral blood effector CD8+ T cells from SSc produce high levels of IL-13. ⺠Dysregulation associated with abnormal expression of GATA-3 nuclear protein. ⺠Critical for predisposing SSc patients to more severe forms of cutaneous disease. ⺠IL-13 and GATA-3 are potential biomarkers of immune dysfunction in SSc.
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Authors
Patrizia Fuschiotti,