Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5898324 | Cytokine | 2011 | 9 Pages |
Abstract
⺠Adipose tissue inflammation is not affected by IL-6 deficiency in mice. ⺠IL-6 KO obese mice do not develop leukocytosis but have reduced platelet numbers. ⺠SAA-1 is the only acute-phase protein that requires IL-6 for induction by obesity.
Keywords
TSP-1MPVTPOLBPPAI-1CeruloplasminHFDDIOAprinflammationvisceral adipose tissuecardiovascular diseaseThrombospondin-1ThrombopoietinThiazole orangeCVDHigh fat dietLeukocytesVATmean platelet volumeObesityPlasminogen activator inhibitor-1HAMPHepcidinAcute-phase responseLPS binding proteinPlateletsdiet-induced obesity
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Authors
Maria Pini, Davina H. Rhodes, Giamila Fantuzzi,