Article ID Journal Published Year Pages File Type
5898367 Cytokine 2011 8 Pages PDF
Abstract
► We reviewed the literature for cytokine profiles in localized scleroderma (LS). ► Though limited in LS, most findings reflect cytokine profiles in systemic sclerosis. ► Both Th1 and Th2 cytokines are found to be elevated in the sera of LS patients. ► Elevated cytokines correlate to clinical data such as LS subtype and disease burden. ► Assessment of disease activity and cytokine profile in the tissue should be considered.
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