Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5898381 | Cytokine | 2011 | 8 Pages |
Abstract
⺠The IL-27 level in synovial fluid of RA is significantly higher than that of OA. ⺠IL-27 in RA joints is derived from CD14+ cells. ⺠IL-27+CD14+ cells significantly infiltrate into RA synovium. ⺠WSX-1 is ubiquitously expressed on RA synovium. ⺠IL-27 suppresses the production of IL-6 or CCL20 from RA fibroblast-like synoviocytes.
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Authors
Shimei Tanida, Hiroyuki Yoshitomi, Masahiro Ishikawa, Takashi Kasahara, Koichi Murata, Hideyuki Shibuya, Hiromu Ito, Takashi Nakamura,