Article ID Journal Published Year Pages File Type
5898393 Cytokine 2011 7 Pages PDF
Abstract
► 1,25(OH)2D3 induced a down-regulation of IL-6, TNFα and IFNγ when stimulated with Mycobacterium tuberculosis. ► IL-10 production and cathelicidin mRNA expression were increased. ► 1,25(OH)2D3 inhibited proinflammatory cytokine response through reduced expression of TLR2, TLR4, Dectin-1 and mannose receptor.
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Preview
Vitamin D3 down-regulates proinflammatory cytokine response to Mycobacterium tuberculosis through pattern recognition receptors while inducing protective cathelicidin production
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