Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5898470 | Cytokine | 2011 | 7 Pages |
Abstract
These data demonstrated that HMGB1 might induce the differentiation of splenic DCs to CD11clowCD45RBhigh DCs followed by shifting of Th1 to Th2 with enhancement of T lymphocyte immune function in vitro. Also, the effect of HMGB1 on T cell differentiation to Th2 was not associated with the inhibition of IL-12 production in CD11chighCD45RBlow DCs.
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Authors
Qing-yang Liu, Yong-ming Yao, Yong-hong Yan, Ning Dong, Zhi-yong Sheng,