Article ID Journal Published Year Pages File Type
5898860 Diabetes Research and Clinical Practice 2016 4 Pages PDF
Abstract

•Irisin levels were significantly elevated after CSII treatment in T2DM patients.•Elevated irisin was accompanied by improved glycemic control and lipid profiles.•Elevated irisin may represent benefits of ameliorative metabolism following CSII.

Irisin, identified as a novel myokine, plays an important role in improving metabolic disorders, including type 2 diabetes mellitus (T2DM). In this interventional study, we investigated the alteration of serum irisin levels in T2DM subjects after transient continuous subcutaneous insulin infusion (CSII) treatment.

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