| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5899953 | Diabetes Research and Clinical Practice | 2013 | 5 Pages |
Abstract
Aqueous humor from T2DM patients with retinopathy exhibits elevated antioxidant activity with significant suppressive effect on ROS production and enhanced levels of locally secreted VEGF and IL-6 in comparison with T2DM patients without retinopathy. These results suggest an inflammatory profile in the absence of typical oxidative stress for T2DM patients with retinopathy, possibly resulting from the compensatory antioxidant response detected in the aqueous humor improving the ocular redox state.
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Authors
Aline A. Fulgêncio Cunha, Adriana A. Bosco, Clara Araújo Veloso, Caroline Maria Oliveira Volpe, Miriam Martins Chaves, José Augusto Nogueira-Machado,