| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5900100 | Diabetes Research and Clinical Practice | 2011 | 6 Pages |
Abstract
Tiliroside isolated from Chinese herb Potentilla chinensis showed therapeutic activities in diabetes. We synthesized 7 tiliroside-derivatives and examined their effects on surface GLUT4myc levels in muscle cells. Derivatives 2a and 3 increased surface GLUT4myc levels, and derivative 3 has the greatest potential. AMPK may be involved in tiliroside-derivatives-regulated GLUT4myc traffic.
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Authors
Lihuan Shi, Nan Qin, Lijuan Hu, Linjuan Liu, Hongquan Duan, Wenyan Niu,