How sensitive is the case definition for diabetic sensorimotor polyneuropathy to the use of different symptoms, signs, and nerve conduction parameters in Type 1 diabetes?

We examined the impact of variation in the interpretation of published guidelines for polyneuropathy diagnosis in type 1 diabetes. Though insensitive to clinical criteria, results indicated that case definition was substantially influenced by variation in electrophysiological criteria emphasizing the need for research into targeted algorithms for incorporation into future guidelines.