Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5900488 | Diabetes Research and Clinical Practice | 2011 | 4 Pages |
Abstract
A randomized, crossover study compared the effects of atorvastatin, gemfibrozil and their combination on inflammatory markers in type 2 diabetes. C-reactive protein (CRP), lipoprotein-associated phospholipase A2 (Lp-PLA2), secretory phospholipase A2 (sPLA2), interleukin 8 (IL8), monocyte chemotactic protein 1 (MCP1) and tumor necrosis factor α (TNFα) were measured. Both lipid-lowering drugs had positive, complementary and additive effects on inflammatory markers, which were closely related to baseline inflammatory status.
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Authors
Ana MarÃa Wägner, Jose Luis Sánchez-Quesada, Sonia BenÃtez, Cristina Bancells, Jordi Ordóñez-Llanos, Antonio Pérez,