Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5900708 | Frontiers in Neuroendocrinology | 2012 | 22 Pages |
Abstract
⺠The paraventricular and supraoptic nuclei of the hypothalamus are regulators of homeostasis. ⺠Over one hundred G protein-coupled receptors are expressed in each of these nuclei. ⺠The receptors have many functions including modulating neuropeptide synthesis and release. ⺠20-30% of the receptors are 'orphans' whose endogenous ligand and function is unknown.
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Authors
Georgina G.J. Hazell, Charles C. Hindmarch, George R. Pope, James A. Roper, Stafford L. Lightman, David Murphy, Anne-Marie O'Carroll, Stephen J. Lolait,