Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5900806 | General and Comparative Endocrinology | 2016 | 35 Pages |
Abstract
Overall, our data indicate that several sirtuins and metabolic genes display specific gene expression trajectories during fetal and early postnatal life. Gene expression alterations observed in IUGR are correlated to IGF-1 dysregulation. Given the importance of the genes studied in metabolic control, their perinatal alterations might contribute to the predisposition to metabolic disease of adulthood.
Keywords
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Endocrinology
Authors
Sabrina Chriett, Isabelle Le Huërou-Luron, Hubert Vidal, Luciano Pirola,