Article ID Journal Published Year Pages File Type
5901330 General and Comparative Endocrinology 2013 32 Pages PDF
Abstract
► Chemokine and opioid GPCRs are simultaneously expressed on leukocytes. ► GPCRs on leukocytes may interact via dimerization or heterologous desensitization. ► Adrenaline, morphine and melatonin inhibit chemokine-induced chemotaxis of phagocytes. ► Specificity and efficacy of medications may be affected by GPCR interactions.
Keywords
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Endocrinology
Preview
Neuroendocrine-immune interaction: Regulation of inflammation via G-protein coupled receptors
Authors
, , ,