Article ID Journal Published Year Pages File Type
5901829 Growth Hormone & IGF Research 2011 7 Pages PDF
Abstract
Our results indicate that the neutrophil-derived preparation of azurocidin contains a protease activity which cleaves IGFBP-1, IGFBP-2 and IGFBP-4. These findings are of interest since both IGFBP-1 and azurocidin increase during inflammation. The effect of azurocidin on IGFBP- and IGF-activity needs to be further investigated.
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Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Endocrinology
Preview
Neutrophil-derived azurocidin cleaves insulin-like growth factor-binding protein-1, -2 and -4
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