Article ID Journal Published Year Pages File Type
5901935 Journal of Diabetes and its Complications 2016 8 Pages PDF
Abstract
Metformin improves the FG-induced endothelial dysfunction in HUVECs. The protective effect of metformin may be mediated through activation of GTPCH1-mediated eNOS recoupling and inhibition of NADPH oxidase via an AMPK-dependent pathway.
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Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Endocrinology
Preview
Metformin attenuates fluctuating glucose-induced endothelial dysfunction through enhancing GTPCH1-mediated eNOS recoupling and inhibiting NADPH oxidase
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