Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5902780 | Journal of Diabetes and its Complications | 2015 | 8 Pages |
Abstract
PEG-FGF21 has a better long-acting efficacy than insulin glargine. PEG-FGF21 achieves glucose clearance by accelerating glycolysis by up-regulating expression of GK and GLUT1 and inhibiting gluconeogenesis via down-regulation of G6Pase and PEPCK expression.
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Authors
Pengfei Xu, Xianlong Ye, Yingjie Zhang, Qingyan Yuan, Mingyao Liu, Qiang Wu, Guiping Ren, Deshan Li,