Nanostructure-based electrochemical sensor for the voltammetric determination of benserazide, uric acid, and folic acid

A carbon paste electrode modified with carbon nanotubes and ferrocene was fabricated. An electrochemical study of the modified electrode and an investigation into its efficiency for the electrocatalytic oxidation of benserazide, uric acid and folic acid were undertaken. The electrode was also used to study the electrocatalytic oxidation of benserazide using cyclic voltammetry, chronoamperometry, and square wave voltammetry (SWV). We found that the oxidation of benserazide at the surface of the modified electrode occurs at a potential about 285 mV lower than that of unmodified carbon paste electrode. SWV gave a linear dynamic range from 8.0×10−7 to 7.0×10−4 mol/L. The detection limit was 1.0×10−7 mol/L for benserazide. This modified electrode was used for the determination of benserazide, uric acid, and folic acid in an urine sample.

Graphical AbstractA new electrochemical sensor based on a ferrocene (FC) modified carbon nanotube paste electrode was constructed for the simultaneous determination of benserazide, uric acid, and folic acid.Figure optionsDownload full-size imageDownload as PowerPoint slide