| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5903027 | Metabolism | 2016 | 8 Pages |
Abstract
Teneligliptin is not only effective as DPP-4 inhibitor, but may also be beneficial as ·OH scavenger, which may be useful in the prevention of diabetic complications.
Keywords
TLCSTZHRMSDPP-48-OHdGXODteneligliptinNOSIC50HpxESRGLP-1DMPOF344Xanthine oxidase8-hydroxy-2′-deoxyguanosineO2−ROS·OHstreptozotocinELISAEnzyme-linked immunosorbent assayOxidative stressDipeptidyl peptidase-4Electron spin resonanceSuperoxidehigh-resolution mass spectrometryRadical scavenging activityFischer 344DPP-4 inhibitornitric oxide synthasehalf maximal inhibitory concentrationhypoxanthineglucagon-like peptide-1thin-layer chromatographyReactive oxygen species
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Endocrinology
Authors
Shinichiro Kimura, Toyoshi Inoguchi, Toshihide Yamasaki, Mayumi Yamato, Makoto Ide, Noriyuki Sonoda, Kenichi Yamada, Ryoichi Takayanagi,