| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5903082 | Metabolism | 2016 | 27 Pages |
Abstract
Î2M mRNA expression in cells of the urinary sediment is higher in T1D patients with DKD and in patients with FSGS in comparison to healthy subjects, maybe reflecting a tubulointerstitial injury promoted by albumin. Given the proinflammatory nature of B2M, we suggest that this protein contributes to diabetic (and possibly, to non-diabetic) tubulopathy.
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Authors
Maria Beatriz Monteiro, Karina Thieme, Daniele Pereira Santos-Bezerra, Márcia Silva Queiroz, Viktoria Woronik, Marisa Passarelli, Ubiratan Fabres Machado, Daniel Giannella-Neto, Maria Oliveira-Souza, Maria Lúcia Corrêa-Giannella,